Using assays for monoclonal m proteins electrophoresis immunofixation and kappa lambda free light chains flcs we determined longitudinally the prevalence of mgus and characterized patterns of monoclonal immunoglobulin abnormalities prior to mm diagnosis. Primary amyloid is caused by a subset of monoclonal free light chains that have the property of forming amyloid fibrils. Mgus short for monoclonal gammopathy of undetermined significance is a condition that causes the body to create an abnormal protein.
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